Space Shuttle Columbia nears its touchdown on Runway 22 at Edwards, California, at 8:39 a.m., 14 June 1991, as the STS-40 life sciences mission comes to an end at NASA's Ames-Dryden Flight Research Facility (later redesignated Dryden Flight Research Center) after nine days of orbital flight. Aboard Columbia during the extended mission were Bryan D. O'Connor, mission commander; Sidney M. Gutierrez, pilot; mission specialists James P. Bagian, Tamara E. Jernigan, and Margaret Rhea Seddon; and payload specialists Francis Andrew Gaffney and Millie Hughes-Fulford. STS-40 was the first space shuttle mission dedicated to life sciences research to explore how the body reacts to a weightless environment and how it readjusts to gravity on return to earth. Columbia was launched on the STS-40 mission 5 June 1991, from Kennedy Space Center in Florida.